Genomic and genetic variation in E2F transcription factor-1 in men with nonobstructive azoospermia
نویسندگان
چکیده
منابع مشابه
Clinical management of infertile men with nonobstructive azoospermia
The clinical management of men with nonobstructive azoospermia (NOA) seeking fertility has been a challenge for andrologists, urologists, and reproductive medicine specialists alike. This review presents a personal perspective on the clinical management of NOA, including the lessons learned over 15 years dealing with this male infertility condition. A five-consecutive-step algorithm is proposed...
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Objective Several recent studies have shown that mitochondrial DNA mutations lead to major disabilities and premature death in carriers. More than 150 mutations in human mitochondrial DNA (mtDNA) genes have been associated with a wide spectrum of disorders. Varicocele, one of the causes of infertility in men wherein abnormal inflexion and distension of veins of the pampiniform plexus is observe...
متن کاملStromal Cell Derived Factor-1 Genetic Variation at Locus 801 in Patients with Myasthenia Gravis
Background: Myasthenia gravis (MG) is the most common disorder of neuromuscular junction in which autoantibodies develop against nicotinic acetylcholine receptor for unknown reasons. The association of immunomodulator genes with different autoimmune disease has been studied in recent years. Objective: The aim of this study was to investigate correlation between a genetic variation in Stromal Ce...
متن کاملOutcome of varicocele repair in men with nonobstructive azoospermia: systematic review and meta-analysis
The objective of this systemic review was to evaluate the benefit of repairing clinical varicocele in infertile men with nonobstructive azoospermia (NOA). The surgically obtained sperm retrieval rate (SRR) and pregnancy rates following assisted reproductive technology (ART) with the use of retrieved testicular sperm were the primary outcomes. The secondary outcomes included the presence of viab...
متن کاملRole of optimizing testosterone before microdissection testicular sperm extraction in men with nonobstructive azoospermia.
PURPOSE Although optimizing endogenous testosterone production before testicular sperm extraction is commonly practiced, whether improved preoperative testosterone levels enhance sperm retrieval remains unclear. We evaluated the influence of preoperative medical therapy in men with nonobstructive azoospermia before microdissection testicular sperm extraction. MATERIALS AND METHODS A total of ...
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ژورنال
عنوان ژورنال: Fertility and Sterility
سال: 2015
ISSN: 0015-0282
DOI: 10.1016/j.fertnstert.2014.09.021